dictyNews

Electronic Edition

Volume 47, number 17

September 3, 2021



Please submit abstracts of your papers as soon as they have been

accepted for publication by sending them to [log in to unmask]

or by using the form at

http://dictybase.org/db/cgi-bin/dictyBase/abstract_submit.



Back issues of dictyNews, the Dicty Reference database and other

useful information is available at dictyBase - http://dictybase.org.



Follow dictyBase on twitter:

http://twitter.com/dictybase





=========

Abstracts

=========





Genetic Instability Due to Spindle Anomalies Visualized in Mutants 

of Dictyostelium



by Mary Ecke, Jana Prassler and Günther Gerisch 





Cells 2021, 10(9), 2240; https://doi.org/10.3390/cells10092240



Aberrant centrosome activities in mutants of Dictyostelium 

discoideum result in anomalies of mitotic spindles that affect the 

reliability of chromosome segregation. Genetic instabilities caused 

by these deficiencies are tolerated in multinucleate cells, which can 

be produced by electric-pulse induced cell fusion as a source for 

aberrations in the mitotic apparatus of the mutant cells. Dual-color 

fluorescence labeling of the microtubule system and the chromosomes 

in live cells revealed the variability of spindle arrangements, of 

centrosome-nuclear interactions, and of chromosome segregation 

in the atypical mitoses observed.





submitted by:  Mary Ecke [[log in to unmask]]

=======================================================

[End dictyNews, volume 47, number 17]