Dear Dicty workers,
please let me pick your brains for the following:
I'd like to redirect cytoplasmic proteins to new places within the cell 
upon a stimulus ( e.g. using a small molecule as a hetero-dimerization 
agent). This could be achieved by having a cytoplasmic recruitee bind to 
a recruiter on an organelle (ER, Golgi, Mitochondria...).
For that to work I'd like help with finding suitable recruiters. In 
other words -  markers for organelles that you or others have used 
successfully in vivo. These proteins should also contain a cytoplasmic 
portion that can tolerate fusion to be useful.

So far I have successfully used calnexin, which however failed later for 
other reasons.

All hints are appreciated!

Thanks a lot,
-Oliver


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o l i v e r   h o e l l e r
postdoc
lim&  weiner labs
ucsf