Hi Daniel-
I would say that they're genetically equal, but physiologically quite  
different due to the cell-cycle dependent and sister cell differences  
in Ca++, cytosolic pH, and levels of proteins such as RtoA.
cheers
Richard Gomer


Quoting Daniel Lusche <[log in to unmask]>:

> Dear all,
> can anyone provide me with a reference for a review or an update on  
> the state of the art whether all cells of a clone (such as a  
> labstrain) are considered to be equal early on in development or  
> whether  the qualitative differences reported by some earlier  
> studies confirm that they are not equal. Any news about what seems  
> to be the case?
> Cheers
> Dan
>
>