The Shwachman-Bodian-Diamond syndrome gene.
The dicty protein, which is essential for ribosome assembly, can be
substituted by the human; disease mutations are defective.
Blood 118, 4305, 2011

Rob

> Dear All
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> Does anyone know of published examples of a Dictyostelium developmental
> mutant being complemented by a Human gene product?
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> Or even more, a gene with a functional role shared between Human and
> Dictyostelium (ie the Human gene complements a Dictyostelium developmental
> mutant and the Dictyostelium gene complements a human null mutant)?
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> Thanks very much
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> Robin
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