Dear Sascha,
In mitochondria of Dictyostelium cells subjected to starvation, apparent large holes, possibly derived from swollen cristae, could be seen by electron microscopy and by electron tomography, as described in Kosta, A, Luciani, M.-F., Geerts, W. and Golstein, P. (2008). Marked mitochondrial alterations upon starvation without cell death, caspases or Bcl-2 family members. Biochimica et Biophysica Acta - Molecular Cell Research, 1783, 2013-2019 http://www.ncbi.nlm.nih.gov/pubmed/18652851
Best regards,
Pierre
____________________________________________________
Pierre Golstein, Centre d'Immunologie de Marseille-Luminy
Case 906, Campus de Luminy, Avenue de Luminy
13288 Marseille cedex 9, France
________________________________________
De : DICTY [[log in to unmask]] de la part de Sascha Thewes [[log in to unmask]]
Date d'envoi : mercredi 12 juin 2013 17:29
Ā : [log in to unmask]
Objet : [DICTY] EM mitochondria
Dear Dicty researchers,
We did in our lab EM pictures of Dicty cells and found some strange looking
mitochondria. Mitos seem to have wholes or inclusions (see arrows in the
attached image). As it is the first time for us to make EM pictures we are
not sure if we just see preparation artefacts or something else. Has anybody
suggestions?
Thanks for your help,
Sascha.
--
Sascha Thewes, PhD
Institute for Biology - Microbiology
Department of Biology, Chemistry, Pharmacy
Freie Universität Berlin
Königin-Luise-Str. 12-16
14195 Berlin
Germany
Phone: +49-(0)30-838-53373
Fax: +49-(0)30-838-57773
Email: [log in to unmask]
Web:
http://www.biologie.fu-berlin.de/arbeitsgruppen/mikrobiologie/ag_mutzel/inde
x.html
|