Dear Jonathan,

In our lab, we evolved AX3 cells for their adhesion to the surface.
We found that evolved cells that are less adhesive to the surface are 
more stick to each other at the starting starvation  but less stick to 
each other during the streaming stage. Whereas evolved cells that 
attached more to the surface are more stick to each other at the 
streaming stage.
You can find our results here about cell-surface adhesion (during growth 
and development in SI) and cell-cell adhesion (during development in 
SI):
https://urldefense.com/v3/__https://www.sciencedirect.com/science/article/pii/S2589004222012780__;!!Dq0X2DkFhyF93HkjWTBQKhk!Xk-9-UEVkdLWLZc5skrrXkdv_xc9jFKPZi746kvvotu-dHj9mWsC7MJZXO1uShodTtslDLA_pFsfmupD49SdYDf6bIMm2F20$  
If you need more information do not hesitate.

Sandrine Adiba


Le 2022-09-29 17:14, Chubb, Jonathan a écrit :
> Dear All,
>  Can any of you recommend any nice clean cell-cell adhesion
> perturbations- ideally those making cells stick to each other more
> than they normally should.
>  Thanks,
>  Jonathan
> 
>  ---
> 
> Professor Jonathan Chubb
> 
> Wellcome Trust Senior Fellow
> 
> UCL Laboratory for Molecular Cell Biology
> 
> University College London,
> 
> Gower Street,
> 
> London
> 
> WC1E 6BT