DICTY Archives

February 2014, Week 3

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Subject:
Re: Dicty World Race Rules
From:
"William F. Loomis" <[log in to unmask]>
Reply To:
DICTY <[log in to unmask]>
Date:
Fri, 21 Feb 2014 17:25:11 -0800
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Monica,

If I were a racing man I would consider entering Dicty mutants in RCK1, 
pde5, or pde6. See Manahan, Iglesias, Long and Devrteotes (2004). see 
page 235 near bottom for RCK1 chemotaxing 50% faster than wild-type 
cells. We would demolish the opposition.

The phosphodiestrases appear to affect cGMP signaling. They have higher 
chemotactic indices than wild type cells (Bosgraat et al. 20002) 
probably as the result of forming fewer lateral pseudopods.

Bill

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